患側甲狀腺全切除+峽部切除術式治療甲狀腺單側結節(jié)的臨床價值探究
發(fā)布時間:2018-06-23 來源: 美文摘抄 點擊:
【摘要】 目的 探究甲狀腺單側結節(jié)行患側甲狀腺全切除及峽部切除術式聯(lián)合治療的臨床價值。方法 94例甲狀腺單側結節(jié)患者作為研究對象, 根據(jù)手術方法不同分為研究組與對照組, 各47例。
對照組患者行傳統(tǒng)手術治療, 研究組患者行患側甲狀腺全切除+峽部切除術式治療, 比較兩組療效、并發(fā)癥及復發(fā)情況。結果 研究組總有效率為95.74%, 明顯高于對照組的78.72%, 差異具有統(tǒng)計學意義(P<0.05)。研究組總并發(fā)癥發(fā)生率為4.26%, 明顯低于對照組的21.28%, 差異具有統(tǒng)計學意義(P<0.05)。隨訪3個月后, 研究組復發(fā)率為2.13%, 明顯低于對照組的19.15%, 差異具有統(tǒng)計學意義(P<0.05)。
結論 患側甲狀腺全切除和峽部切除術式協(xié)同治療可促進療效提升, 且并發(fā)癥發(fā)生率低, 可推廣。
【關鍵詞】 甲狀腺單側結節(jié);峽部切除術;患側甲狀腺全切除;療效
DOI:10.14163/j.cnki.11-5547/r.2018.12.010
【Abstract】 Objective To investigate the clinical value of total thyroidectomy of affected side combined with isthmectomy in the treatment of unilateral thyroid nodules. Methods A total of 94 patients with unilateral thyroid nodules as study subjects were divided by different surgical methods into research group and control group, with 47 cases in each group. The control group received traditional surgical therapy, and the research group received total thyroidectomy of affected side + isthmectomy. Comparison were made on efficacy, complications and recurrence between the two groups. Results The research group had obviously higher total effective rate as 95.74% than 78.72% in the control group, and the difference was statistically significant (P<0.05). The research group had obviously lower incidence of total complications as 4.26% than 21.28% in the control group, and the difference was statistically significant (P<0.05). After 3 months of follow-up, the research group had obviously lower recurrence rate as 2.13% than 19.15% in the control group, and the difference was statistically significant (P<0.05). Conclusion Combined therapy of total thyroidectomy of affected side and isthmectomy can promote the efficacy with low incidence of complications, and it can be promoted.
【Key words】 Unilateral thyroid nodules; Isthmectomy; Total thyroidectomy of affected side; Efficacy
甲狀腺單側結節(jié)為臨床一種常見病, 一般為體檢時發(fā)現(xiàn), 無自覺癥狀, 且多發(fā)人群為中年女性。甲狀腺單側結節(jié)發(fā)生率占甲狀腺結節(jié)疾病90%, 通常為良性, 但約有5%顯示為惡性病理[1]。目前, 臨床常予以手術治療, 但因甲狀腺腫瘤源頭具多中心特點, 采取傳統(tǒng)手術切除治療, 術后病變復發(fā)率較高, 影響患者預后。隨著醫(yī)療技術水平提升, 甲狀腺結節(jié)疾病研究深入, 患側甲狀腺全切除加峽部切除術治療方式逐漸應用于臨床, 但其手術療效仍具爭議性。本研究為明確峽部切除術+患側甲狀腺全切除用于甲狀腺單側結節(jié)治療的效果, 本院針對性選取94例患者資料予以分析, 并報告如下。
1 資料與方法
1. 1 一般資料 選取2015年2月~2017年8月收治的94例
甲狀腺單側結節(jié)患者作為研究對象, 將臨床資料完整、無認知功能障礙者納入, 將并發(fā)血液系統(tǒng)疾病、肝腎功能嚴重障礙者排除。根據(jù)手術方法不同將患者分為研究組與對照組, 各47例。對照組男女比例20∶27;年齡31~62歲, 平均年齡(46.75±13.19)歲;體重45~78 kg, 平均體重(59.13±15.11)kg。
研究組男女比例19∶28;年齡32~63歲, 平均年齡(46.76±
13.21)歲;體重46~79 kg, 平均體重(59.27±15.24)kg。兩組患者一般資料比較差異無統(tǒng)計學意義(P>0.05), 具可比性。
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